From 8e807b8d14613557124e73f10de46d1089cf5acb Mon Sep 17 00:00:00 2001 From: pasqualehornib Date: Fri, 3 Apr 2026 02:04:55 +0800 Subject: [PATCH] Add Androgen insensitivity syndrome Wikipedia --- Androgen-insensitivity-syndrome-Wikipedia.md | 9 +++++++++ 1 file changed, 9 insertions(+) create mode 100644 Androgen-insensitivity-syndrome-Wikipedia.md diff --git a/Androgen-insensitivity-syndrome-Wikipedia.md b/Androgen-insensitivity-syndrome-Wikipedia.md new file mode 100644 index 0000000..eddd124 --- /dev/null +++ b/Androgen-insensitivity-syndrome-Wikipedia.md @@ -0,0 +1,9 @@ +
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Molecular diagnosis is achieved in almost all patients with CAIS and in a lower frequency in PAIS individuals. Non-synonymous point mutations are the commonest AR defects reported in AIS. In MAIS, the diagnosis should be considered in cases of pubertal gynecomastia and male infertility. In PAIS, the diagnosis is usually at birth due to the atypical external genitalia. In CAIS, the diagnosis can be done intrauterus, at birth, childhood or [https://li1420-231.members.linode.com/jmusabrina3852/getchefpahadi.com2004/wiki/Buy-Testosterone-Enanthate-online,-cheap-injection-for-sale](https://li1420-231.members.linode.com/jmusabrina3852/getchefpahadi.com2004/wiki/Buy-Testosterone-Enanthate-online%2C-cheap-injection-for-sale) after puberty. Gender change is very rarely described in CAIS and there are just four cases of gender change in individuals with CAIS (57). +However, they too may be carriers and be able to pass the AIS gene on to any children they have. This means she's a carrier of the AIS gene, but does not have AIS and is able to have children. As the mother has 2 X chromosomes, the normal chromosome is able to make up for the faulty one. The AIS gene is found on the mother's X chromosome. Females usually have 2 X chromosomes (XX), while males usually have an X and a Y chromosome (XY). This depends on the pair of sex chromosomes they receive from their parents and their ability to respond to the sex hormones they make. It controls the development of the usual changes expected in boys, [https://date.etogetherness.com/@eusebiachidley](https://date.etogetherness.com/@eusebiachidley) such as penis growth and [http://207.180.227.11/](http://207.180.227.11:3001/dorethadumont) the testicles moving down into the scrotum. +Disorders of sex development are recognized as a risk factor for type II germ cell tumors (GCTs). In male AIS, at pubertal age, high [buy testosterone cypionate](https://tovegans.tube/@lachlanseward7?page=about) doses (200–500 mg twice a week) can be used, in order to increase the penile size and to promote virilization (1). Genitoplasty is usually necessary in PAIS females and estrogen replacement is mandatory at pubertal time, with similar recommendation as describe for CAIS patients (15). There are many vaginoplasty techniques (34), [43.143.209.246](http://43.143.209.246:6300/weldonspinks8) but non-surgical dilation is effective, safe, [eram-jobs.com](https://eram-jobs.com/employer/9-signs-of-low-testosterone-in-men) non expensive and normalizes vaginal length and sex intercourse (32). So far, gonadectomy is performed at early age, in order to avoid the risk of malignancies and the psychosocial difficulties in submitting an adolescent female to gonadectomy (24). +[buy testosterone injections](https://lovewiki.faith/wiki/User:KimSteel63) is the sex hormone produced by the testicles. As such, affected individuals do not menstruate and are unable to conceive a child (infertile). It’s important to talk with your child about their AIS around the time of puberty. Sometimes, they wait until puberty to choose one. But some health experts think certain treatments, [theudtaullu.com](https://theudtaullu.com/@leoladenovan6?page=about) such as removal of the testicles, should happen before puberty. This gives your child’s body time to go through developmental changes. But CAIS (complete AIS) or MAIS might not be evident until the age of 11 or 12, when puberty begins. +But they may have female genitals or a combination of male and [heywhatsgoodnow.com](https://heywhatsgoodnow.com/@lilianadunham) female genitals. You may struggle to have a normal sex life or find a partner who understands and accepts your condition. These tests can tell you if you’re a carrier of the abnormal gene. +Scientists aren’t sure if and [whiskey.tangomedia.fr](https://whiskey.tangomedia.fr/@pqiterrie44340?page=about) how DHT affects females, but they think it may play a role in body hair and pubic hair growth. [buy testosterone propionate](https://tiktub.com/@marianhop74537?page=about) levels may be elevated despite normal levels of luteinizing hormone. MAIS is only diagnosed in normal phenotypic males, and is not typically investigated except in cases of male infertility. Although technically a variant of MAIS, SBMA's presentation is not typical of androgen insensitivity; symptoms do not occur until adulthood and include neuromuscular defects as well as signs of androgen inaction. +Androgen insensitivity syndrome isn’t life-threatening. Androgen insensitivity syndrome is a hereditary condition, meaning it’s passed down from the mother to the child. AIS was previously called testicular feminization syndrome. AIS can cause problems during puberty, as well as infertility as an adult. Fertility was described in one PAIS individuals, and therapeutic strategy for successful fertility could be experienced in PAIS and MAIS individuals. For males with PAIS, the testis should be placed in the scrotum and regularly monitored. +
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